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The 10 AI breakthroughs reshaping our world in 2025

By Leo Martins
November 2, 2025
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News / Brain cells beat AI in learning speed and efficiency: What this means for the future of intelligence
NewsResearch

Brain cells beat AI in learning speed and efficiency: What this means for the future of intelligence

Daniel Reed
ByDaniel Reed
AI Research, Safety & Ethics Analyst
Daniel Reed currently works as an AI Research, Safety & Ethics Analyst at Aiholics, writing about how changes in artificial intelligence are affecting and will affect...
- AI Research, Safety & Ethics Analyst
Published: August 12, 2025
5 Min Read
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It’s often said that artificial intelligence is modeled after the human brain, but what if the brain itself could inspire entirely new kinds of AI – ones that actually learn faster and more efficiently than our best machine learning algorithms? I recently came across a fascinating study that showed just that, using living neural cells to outpace traditional AI in learning tasks. This isn’t science fiction; it’s the cutting edge of biological computing.

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How living brain cells outperform machine learning

The team behind this breakthrough, including the Melbourne startup Cortical Labs, developed a system called DishBrain that merges live human-derived neurons with silicon chips. This hybrid setup forms what they call Synthetic Biological Intelligence (SBI). What’s truly remarkable is that when these living neural cultures were put into a game environment – essentially a Pong simulation – their learning speed and adaptability beat some of the most advanced reinforcement learning (RL) algorithms, including DQN, A2C, and PPO.

Why does this matter? Because unlike AI systems that often require millions of training steps to improve, these biological networks reorganized in real-time, adapting rapidly to stimuli with far fewer samples. This sample efficiency mimics how real brains learn – quickly, flexibly, and with greater connectivity plasticity. It’s a huge leap in understanding how biological intelligence can potentially eclipse traditional AI in some areas.

These biological systems not only adapt faster but do so more efficiently and robustly when learning opportunities are limited – closer to how humans actually learn.

The birth of bioengineered intelligence: two paths, one exciting future

The implications extend beyond just beating AI at one game. Cortical Labs and partnering research institutes have articulated a new paradigm called Bioengineered Intelligence (BI). This approach uses engineered neural circuits within cultured brain cells to develop intelligence, contrasting with but complementing a related field called Organoid Intelligence (OI), which relies on brain organoids.

This dual-path framework essentially opens up a new frontier where biological substrates can be harnessed for computation and intelligent behavior. By combining living neurons’ dynamic plasticity with cutting-edge electronics and algorithms, BI aims to create systems that not only learn faster but can tackle problems that conventional AI struggles with, especially where adaptability and rapid reconfiguration matter.

Experts find this especially exciting because it integrates principles from neuroscience and machine learning, offering a more ethically sustainable and biologically faithful route toward developing intelligence in machines. It’s a field still in its infancy, but with huge potential for breakthroughs in both understanding the brain and developing revolutionary computing paradigms.

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What this means for AI, neuroscience, and beyond

The proof-of-concept demonstrated with the DishBrain platform and the subsequent launch of the CL1 biological computer signal something profound: intelligence isn’t just code running on hardware; it’s deeply rooted in biological processes. The rapid, adaptive learning observed in living neural cultures suggests that actual intelligence may always remain biological at its core, even as we strive to build smarter machines.

For AI researchers, this doesn’t mean abandoning existing algorithms but rather enriching AI with biological insights that could lead to more sample-efficient, flexible systems. For neuroscientists, it offers a new window into how neural circuits organize, learn, and adapt—not just in brains, but in engineered systems capable of real-time, closed-loop interaction.

Moreover, the technology opens doors to studying neural disorders and brain function with unprecedented precision by creating living models of neural networks that reflect real-world dynamics. This can accelerate developing treatments for neurodegenerative diseases and cognitive conditions.

  • Living neural networks outperform deep RL in learning speed and efficiency under real-world sample constraints.
  • Bioengineered Intelligence emerges as a new paradigm coupling biology and machine intelligence.
  • Understanding biological learning mechanisms can revolutionize AI design and neuroscience research.

Looking forward, the intersection of biology and AI promises a future where machines might not just simulate intelligence but actually embody living, adapting intelligence. This could redefine what we consider a computer, a brain, and the very nature of intelligence itself.

It’s an exciting, humbling reminder that while AI has made incredible strides, the biological brain still holds many keys that machines have yet to unlock. The journey of blending life and machine has only just begun.

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ByDaniel Reed
AI Research, Safety & Ethics Analyst
Daniel Reed currently works as an AI Research, Safety & Ethics Analyst at Aiholics, writing about how changes in artificial intelligence are affecting and will affect scholarship, society, and human civilization. He reports on breakthroughs in AI research, the development of safety frameworks, discussion of long-term risks, and ethical challenges; he also reports on global shifts in policy and governance. Daniel aims to make complex research papers and long-term thinking accessible to the everyday reader without sacrificing nuance. With his thoughtful and analytical style of writing, Daniel translates advanced topics into clear language. He targets questions that really matter: how safe are today's AI systems, what kind of ethical boundaries do we need, and how could exponential progress affect the way education, jobs, governance, and human values are shaped? His articles are often not just expert opinions but also balanced views and insight into emerging debates that define AI's place in the world. Daniel believes responsible AI development begins with awareness, transparency, and informed public conversation. In terms of his work with Aiholics, he encourages readers to look beyond headlines to understand the promise of artificial intelligence but also some of its consequences.
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